Tuesday, April 7, 2020

Where are the recoveries?



All numbers below are based on yesterday’s reported figures of total confirmed cases, total deaths and total recoveries, published on Worldometers.info. I’m happy to send my spreadsheet that calculates all of these to anyone who wants to check the calculations, although they follow the assumptions described below.

I. Numbers based on total cases, actual and projected
Total US confirmed cases: 367,659
Increase in cases since previous day: 30,818 (vs. 25,214 increase yesterday)
Percent increase in cases since yesterday: 9% (vs. 8% yesterday)
Percent increase in cases since 3 days previous: 32% (vs. 37% yesterday)

“Set in stone” US deaths* over course of pandemic:  216,390 (based on 4% case mortality rate)
*This number assumes a) Total cases grow by 30% into the future (= yesterday’s 3-day growth rate in cases); b) We impose a massive lockdown, with prohibition of all non-essential travel, today; c) New cases drop to zero in 28 days, because of the lockdown, but they continue to grow at the current projected rate up to the 28th day; d) testing is widely available by the 28-day mark; and e) case mortality rate = 4%. To consider a 6% mortality rate, multiply each projection by 1.5. For 8%, double it. For comparison, Italy’s case mortality rate is currently 11.75%.

Projected as of April 14 (7 days from today):
These numbers answer the question: What would happen if we wait seven days to totally lock down the US, based on the assumptions below (which frankly are themselves wildly optimistic).
Total expected cases*: 774,747 (vs. 801,329 expected yesterday)
Total expected deaths set in stone* over course of pandemic: 411,521 (vs. 589,040 expected yesterday)
* The expected cases and deaths set in stone numbers assume a) Total cases grow by 32% into the future (= yesterday’s 3-day growth rate in cases); b) We impose a massive lockdown, with prohibition of all non-essential travel, on April 14; c) New cases drop to zero 28 days later, because of the lockdown, but they continue to grow at the current projected rate up to the 28th day; d) Testing is widely available by the 28-day mark; and e) case mortality rate = 4%. To consider a 6% mortality rate, multiply each projection by 1.5. For 8%, double it. For comparison, Italy’s case mortality rate is currently

Projected as of April 21 (14 days from today):
These numbers answer the question: What would happen if we wait 14 days to totally lock down the US, based on the assumptions below (which frankly are themselves very optimistic)?
Total expected cases*: 1,473,380 (vs. 1,625,701 projected yesterday)
Total deaths set in stone* over course of pandemic: 1,248,242 (vs. 802,265 projected yesterday)
* The expected cases and deaths set in stone numbers assume a) Total cases grow by 32% into the future (= yesterday’s 3-day growth rate in cases); b) We impose a massive lockdown, with prohibition of all non-essential travel, on April 21; c) New cases drop to zero in 28 days, because of the lockdown, but they continue to grow at the current projected rate up to the 28th day;; d) Testing is widely available by the 28-day mark; and e) case mortality rate = 4%. To consider a 6% mortality rate, multiply each projection by 1.5. For 8%, double it. For comparison, Italy’s case mortality rate is currently 11.75%.

Date on which 500,000 deaths will be set in stone: April 17  
Date on which 1 million total pandemic deaths will be set in stone: April 24
Number of deaths set in stone on April 30: 1,845,184 (vs. 3,603,124 estimated yesterday)


II. Numbers based on total deaths, reported and projected
Total US deaths as of yesterday: 10,943
Increase in deaths since previous day: 1,323 (vs. 1,625 yesterday)
Percent increase in deaths since previous day: 14% (vs. 14% yesterday)
* Projected deaths = previous day’s new deaths number, grown by that day’s 3-day percentage growth rate. Note this is calculated completely differently from the deaths set in stone, which refers to projected deaths over the entire pandemic, and is calculated by multiplying expected cases by the mortality rate

Date on which the number of new deaths on that day will probably exceed the toll of Sept. 11: April 13
Projected* number of actual deaths on 4/14 alone: 3,780
Projected* number of actual deaths on 4/21 alone: 9,395
Number of deaths on that day on April 30: 30,455


III. Reported case mortality rate so far in the pandemic in the US:
These numbers are also unaffected by the error I made.
Total Recoveries in US as of yesterday: 19,814
Total Deaths as of yesterday: 10,943
Deaths so far as percentage of closed cases (=deaths + recoveries): 36% Let’s be clear. This means that, of all the coronavirus cases that have been closed so far in the US, 36% of them have resulted in death (compare that to the 4% mortality rate I’ve been using to calculate total pandemic deaths, based on total cases). Of course, this number will come down as time goes on and more cases are closed in which the victim recovered. But it’s only come down by about 4 percentage points since Worldometers started publishing the recovery rate on March 26, and on about half the days, it’s gone up; there is still no sign of a downward trend. I’d say it’s much more likely my 4% mortality rate will turn out to be too low, after the pandemic’s over and all of the bodies have been counted, than it will be too high.


One observation, before I get to my main topic for today. Yesterday, the three-day percent changes of both total cases and total deaths fell – these are the two actual numbers that I derive all of my projections from. And you can see that a lot of my projections fell significantly. For example, my projection of total deaths on April 30 alone fell from about 80,000 to 30,000. This is good news, right? It sure is – if you consider a one-week postponement of Armageddon to me good news. But the day on which we’ll pass one million set in stone deaths is about five days after the day I projected yesterday, and the difference for further milestones like two million is also less than a week.

That’s the problem with exponential growth. You have to stop it cold; even a fairly small rate of growth will still result in huge absolute increases later on. So how can we stop the coronavirus cold? Through a complete lockdown for at least one month and probably more, along with a massive rollout of testing (where we can test every citizen multiple times). Anything less than that will never solve the problem. End of today’s sermon.

I wish to focus today on reported recoveries from Covid-19 in the US. Worldometers just started publishing this number on March 26; it sums up recoveries reported by different jurisdictions (I presume states). I use it to calculate the “Deaths so far as percentage of closed cases” number shown above. The formula is very simple: Add total recoveries to total deaths to get total closed cases, then divide total deaths by total cases.

This number answers the question “Of all the people who have gotten sick with Covid-19 so far in the US, what percentage have died?” And here’s the problem: On March 26, that number was 41%. I (and my friend Kevin Perry, who has discussed a lot of these issues with me) thought this would surely come down.

There are good reasons why it has to come down. Perhaps the biggest is that, to confirm that someone is free of the virus, the hospital has to administer two tests. But with tests being in very short supply (and the wait time for a reading varying from 1-2 weeks), many hospitals are very reluctant to use up two tests confirming something they can see clearly just from looking at the patient: they have recovered. Also, in case you haven’t read the news, a lot of hospitals are very busy now. To devote precious time to just certifying that a patient – who has probably already gone home – is virus free seems almost criminal, given there are people in acute need who probably could use all the attention they can give them.

But the problem is, the number hasn’t come down significantly. Since March 29, it’s been fluctuating in the 35-37% range up and down (today it’s up). I’m still sure it will come down a lot sooner or later, but if you look at other countries, they seem to be in the same situation. Italy’s rate is 42%. France’s is 34%. Spain is lower at 24%, but that’s very high. South Korea is at 3%, but of course they had widespread testing available very early and have managed the epidemic extremely well.

I’m using a rate of 4% as the case mortality rate for the US, and I’ve taken a fair amount of heat from people who say that’s too high. But when I compare it to 36% and consider that number has barely changed in two weeks, I’m wondering whether it should be higher than that.

The mortality rate is included in my calculation of the “set in stone” death numbers, not the daily deaths numbers, which are generated by growing the current number by the 3-day rate of change. My methodology for calculating the set in stone numbers is described above, but the key part is that the mortality rate is multiplied by the total number of cases 28 days after the measurement date (i.e., today’s set in stone number of 216,390 equals the total expected cases on May 4 times .04). So if the mortality rate doubles to 8%, then every set in stone deaths number above needs to be doubled. If it goes to 6%, those numbers need to be multiplied by 1.5. And if you consider a 24% rate like Spain’s, you need to multiply each number by six, which would mean that more than 1.2 pandemic deaths are already set in stone in the US.

What do I believe the real rate will turn out to be, once the pandemic’s over and we presumably know all of the deaths (deaths are likely to be underestimated for various reasons, but nothing like the degree to which cases are surely underestimated now)? I don’t know. But I do know that the most worrisome consideration in all of the projections I’m making is this one.

BTW, I put up a post last week that mentioned in the title there were three “windows” into total pandemic deaths, but one was too horrifying to even discuss. Well, this is it.

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